what is chromosome 21

what is chromosome 21 Chromosome 21 is the smallest human chromosome spanning about 48 million base pairs the building blocks of DNA and representing 1 5 to 2 percent of the total DNA in cells Learn about health implications of genetic changes

About 95 percent of the time Down syndrome is caused by trisomy 21 the person has three copies of chromosome 21 instead of the usual two copies in all cells This is caused by abnormal cell division during the Down syndrome or Down s syndrome also known as trisomy 21 is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21 It is usually associated with developmental delays mild to moderate intellectual disability and characteristic physical features

what is chromosome 21

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what is chromosome 21
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Down syndrome is a chromosomal condition related to chromosome 21 It affects 1 in 800 to 1 in 1000 live born infants What are the symptoms of Down syndrome People who have Down syndrome have learning difficulties mental disability a characteristic facial appearance and poor muscle tone hypotonia in infancy Down syndrome is caused by an extra chromosome 21 Children with Down syndrome have delayed physical and mental development specific head and facial features and are often short Before birth Down syndrome may be suspected based on ultrasonography or tests on the mother s blood and confirmed using chorionic villus sampling and or

Down syndrome is a condition in which a person has an extra copy of chromosome 21 Chromosomes are small packages of genes in the body s cells which determine how the body forms and functions When babies are growing the extra chromosome changes how their body and brain develop Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on chromosome 21 either in whole trisomy 21 or part such as due to translocations The effects of the extra copy varies greatly from individual to individual depending on the extent of the extra copy genetic background

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Chromosome 21 is the smallest human chromosome and procedures for examining human chromosomes were still being developed during the first part of the century The sequence of chromosome 21 was a turning point for the understanding of Down syndrome Comparative genomics is beginning to identify the functional components of the chromosome

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what is chromosome 21 - Down syndrome is a chromosomal condition related to chromosome 21 It affects 1 in 800 to 1 in 1000 live born infants What are the symptoms of Down syndrome People who have Down syndrome have learning difficulties mental disability a characteristic facial appearance and poor muscle tone hypotonia in infancy