14 3 3 gene function

14 3 3 gene function 14 3 3 function The human 14 3 3 family consists of seven isoforms and each expressed by a different gene The multiplicity of 14 3 3 isoforms appears

In this review 14 3 3 cDNA cloning nucleotide sequence of 14 3 3 cDNA the structure of 14 3 3 gene and 14 3 3 gene expression in situ hybridization of 14 3 3 mRNA in the brain the Structure and Function of 14 3 3 Proteins The 14 3 3 proteins are a family of highly conserved scaffold proteins They are expressed in various types of tissues 41 45 In mammals seven 14 3 3 isoforms encoded by different genes

14 3 3 gene function

14 3 3 gene function
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PDF Integration Profiling Of Gene Function With Dense Maps Of
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PDF FuncBase A Resource For Quantitative Gene Function Annotation
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Functions of 14 3 3 in proliferative oncogenic survival and stress signaling a Under proliferative signaling conditions 14 3 3 binding is required for the Ras dependent The 14 3 3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells A striking feature of the 14 3 3 proteins is their ability to bind a multitude of functionally

The crystal structure of the Nth1 14 3 3 complex the first example of a 14 3 3 complex with a multidomain partner demonstrated the ability of 14 3 3 proteins to modulate interdomain Domain Binding and Function 14 3 3 genes encode an ubiquitous family of highly conserved acidic proteins of 30 kDa that are found in eukaryotic lineages as diverse as fungi plants and animals

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14 3 3 gene If a 14 3 3 gene knockout mouse could be constructed the function of 14 3 3 in the central nervous system could be clarified However recently Skoulakis and Davis reported We performed genome wide identification and analysis of the 14 3 3 family genes in tomato To explore the properties of the thirteen Sl14 3 3 found in the tomato genome their

The effects of 14 3 3 proteins on their targets can be broadly defined using three categories i conformational change ii physical occlusion of sequence specific or structural protein features and iii scaffolding Of all the 14 3 3 genes 14 3 3 has been most directly linked to cancer It is thought to function as a tumour suppressor by inhibiting cell cycle progression and by

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Figure 1 From The Structure Of The Gene Coding For The Mouse Cell
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14 3 3 gene function - The 14 3 3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells A striking feature of the 14 3 3 proteins is their ability to bind a multitude of functionally